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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 8
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Original Articles

Preparation and Epoxidation of Conjugated Lactams: Influence of Ring Size on Epoxidation

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Pages 1265-1275 | Received 11 Oct 1994, Published online: 23 Sep 2006
 

Abstract

α,β-Epoxy-lactams can be prepared from conjugated lactams by treatment with m-chloroperoxybenzoic acid. Good yields are obtained, however, only with 2-pyrrolidinone derivatives. The yield of epoxy-lactam diminishes dramatically as the size of the lactam ring increases.

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