A Versatile Procedure for the Preparation of Aryl Thiocyanates Using N-Thiocyanatosuccinimide (NTS)

F. Dean Toste J. Tuzo Wilson Laboratories, Erindale College, University of Toronto in Mississauga, Mississauga, Ontario, Canada, L5L 1C6

Vittorio De Stefano J. Tuzo Wilson Laboratories, Erindale College, University of Toronto in Mississauga, Mississauga, Ontario, Canada, L5L 1C6

Ian W. J. Still J. Tuzo Wilson Laboratories, Erindale College, University of Toronto in Mississauga, Mississauga, Ontario, Canada, L5L 1C6

Abstract

A mild procedure for the thiocyanation of several types of arene substrate using N-thiocyanatosuccinimide (NTS) is described. The method appears generally applicable to benzenoid substrates with a wide range of substituents, as well as to heteroaromatic analogues such as indoles and thiophenes.

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A Versatile Procedure for the Preparation of Aryl Thiocyanates Using N-Thiocyanatosuccinimide (NTS)

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A Versatile Procedure for the Preparation of Aryl Thiocyanates Using N-Thiocyanatosuccinimide (NTS)

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