![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
Abstract
An efficient method for the preparation of 2-(chloromethyl)acrylonitrile (7) is reported. The Mannich reaction of cyanoacetic acid with paraformaldehyde and morpholine afforded the allylic amine 6a which was converted into the chloride 7 on treatment with isobutyl chloroformate at room temperature.