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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 16
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Original Articles

A Convenient, Large Scale Synthesis of N-CBZ-(S-Phenyl)-L-Cysteine

Gifford Marzoni Agouron Pharmaceuticals, Inc., 3565 General Atomic Court, San Diego, CA, 92121
,
Stephen W. Kaldor Lilly Research Laboratories, Eli Lilly and Co., Lilly Corporate Center, Indianapolis, IN, 46285
,
Anthony J. Trippe Agouron Pharmaceuticals, Inc., 3565 General Atomic Court, San Diego, CA, 92121
,
Brian M. Shamblin Agouron Pharmaceuticals, Inc., 3565 General Atomic Court, San Diego, CA, 92121
&
James E. Fritz Lilly Research Laboratories, Eli Lilly and Co., Lilly Corporate Center, Indianapolis, IN, 46285
Pages 2475-2482 | Received 03 Jan 1995, Published online: 04 Jan 2007
 
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Abstract

N-Cbz-(S-phenyl)-L-cysteine (3) has been prepared on a multi-kilogram scale in high yield and optical purity from the β-lactone of N-Cbz-L-serine.

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