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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 11
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Original Articles

A Simple Approach to the Synthesis of Fluoren-9-Ones

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Pages 1751-1760 | Received 28 Sep 1994, Published online: 23 Sep 2006
 

Abstract

Cyclohexene-l-Carboxylic acid (I) undergoes reaction with various aromatic substrates (2a-i) in presence of Polyphosphoric acid (PPA) at 100[ddot]c to give cis-1,2,3,4,4a,9a - hexahydrofluoren-9-ones (3a-i) in good yield. Dehydrogenation of (3a-i) with selenium powder afforded corresponding fluoren-9-ones (4a-i) in high yield.

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