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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 10
143
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Original Articles

Improved Preparation of (R) and (S)-3-Aminoquinuclidine Dihydrochloride

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Pages 2009-2015 | Received 15 Nov 1995, Published online: 21 Aug 2006
 

Abstract

An improved procedure for the synthesis of either (R) or (S)-3-aminoquinuclidine was developed. Key intermediate imine 2 was made in a one pot process using lithium oxide as the base and molecular sieves.

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