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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 6
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Original Articles

Base Induced Intramolecular Cyclization of Ã-Ketoimidoyl Chloride—An Efficient Preparation of 2-ACYL 5-Ethoxy Oxazoles

Wei-Sheng Huang Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai, 200032, China
,
Yi-Xin Zhang Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai, 200032, China
&
Cheng-Ye Yuan Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai, 200032, China
Pages 1149-1154 | Received 21 Jun 1995, Published online: 21 Aug 2006
 
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Abstract

The Ã-ketoimidoyl chlorides resulted from the reaction of acyl chlorides with ethyl isocyanoacetate provides 2-acyl 5-ethoxyoxazoles in moderate yields via a base-induced intramolecular cyclization.

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