Synthesis of Glutathione Analogues, Peptide Nucleic Acids and Phosphonooligopeptides from Heterocyclic Imines

Abstract

Synthesis of the title compounds 4, 6 and 8 are described. The glutathione analogues 4 and peptide nucleic acids 6 were prepared from 3-thiazolines according to the Ugi 4CC-reaction. The phosphonooligopeptides 8 were prepared from N, S-and N, O-heterocyclic imines according to the Arbusov reaction.