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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 19
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Original Articles

Synthesis of 2-Methyl-5-nitroimidazol-1-yl-acetaldehyde

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Pages 3653-3657 | Accepted 14 Apr 1996, Published online: 21 Aug 2006
 

Abstract

Pure 2-methyl-5-nitroimidazol-1-yl-acetaldehyde was synthesized by modified Swern oxidation. This compound can be utilized as reaction intermediate in the synthesis of bioreductive agents (e.g., hypoxic cell radiosensitizers, antibiotics against anaerobic organisms).

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