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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 16
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Original Articles

One-Pot Preparation of 1,3-Dihydro-1-(trifluoromethyl)isobenzofuran-1-ol Derivatives from 1,2-Dibromobenzene

Daniel P. Becker Department of Chemistry, Searle Research & Development, 4901 Searle Parkway, Skokie, IL, 60077, USA
,
Hui Li Department of Chemistry, Searle Research & Development, 4901 Searle Parkway, Skokie, IL, 60077, USA
&
Daniel L. Flynn Department of Chemistry, Searle Research & Development, 4901 Searle Parkway, Skokie, IL, 60077, USA
Pages 3127-3135 | Received 22 Mar 1996, Published online: 21 Aug 2006
 
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Abstract

A one-pot method for the preparation of 1,3-dihydro-1-(trifluoromethyl)isobenzofuran-1-ol derivatives 5 from 1,2-dibromobenzene is described.

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