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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 27, 1997 - Issue 7
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Original Articles

Lipase-Mediated Resolutions of 1-Aryl-3-Buten-1-ols

, &
Pages 1217-1222 | Received 29 Jul 1996, Published online: 22 Aug 2006
 

Abstract

Racemic mixtures of 1-aryl-3-buten-1-ols were separated with high enantioselectivity by a lipase-mediated acetylation with vinyl acetate. The effects of the nature, position, and spatial requirements of the phenyl-ring substituents on the separation efficacy were investigated.

Notes

According to Amano Co. private communication, YS and AK lipases are the same preparations from Pseudomonas fluorescens.

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