Abstract
Racemic mixtures of 1-aryl-3-buten-1-ols were separated with high enantioselectivity by a lipase-mediated acetylation with vinyl acetate. The effects of the nature, position, and spatial requirements of the phenyl-ring substituents on the separation efficacy were investigated.
Notes
According to Amano Co. private communication, YS and AK lipases are the same preparations from Pseudomonas fluorescens.