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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 27, 1997 - Issue 24
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Original Articles

Synthesis of Some New γ-N-[(Arylidene-aminoethyl)aminoethyl]aminopropyl-2,8,9-trioxa-5-aza-1-silabicyclo[3,3,3]undecanes

Ji-Mao Lin Department of Chemistry, Shandong University, Jinan, 250100, P. R. China
,
Bin Wang Department of Chemistry, Shandong University, Jinan, 250100, P. R. China
,
Yu-Ying Liu Department of Chemistry, Shandong University, Jinan, 250100, P. R. China
,
Yi-Gui Wang Department of Chemistry, Shandong University, Jinan, 250100, P. R. China
&
Yu-Dao Ma Department of Chemistry, Shandong University, Jinan, 250100, P. R. China
Pages 4309-4314 | Received 05 Jun 1997, Published online: 22 Aug 2006
 
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Abstract

Abstract: Five new γ-N-[(arylideneaminoethyl)aminoethyl]aminopropyl-2,8,9-trioxa-5-aza-1-silabicyclo[3,3,3]undecanes have been synthesized from γ-chloropropyltriethoxysilane and characterized by elemental analyses, IR and 1H NMR. Tests of antitumor activity show that γ-N-[(2-chloro-5-nitrobenzylideneaminoethyl)aminoethyl]aminopropyl-2,8,9-trioxa-5-aza-1-silabicyclo[3,3,3]undecane exhibits biological activity against K562 oncotytes of erythroleukmia.

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