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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 27, 1997 - Issue 11
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Original Articles

An Alternative Preparation of Camptothecin 20(S)-Acetate

Zhisong Cao The Stehlin Foundation for Cancer Research, 1918 Chenevert Street, Houston, Texas, 77003
Pages 2013-2019 | Received 12 Jan 1997, Published online: 22 Aug 2006
 
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Abstract

Camptothecin 20(S) acetate was obtained in 60% yield by reaction of camptothecin with trichloroethane in sulfuric acid. This method represents another alternative preparation of camptothecin ester using trichloroethane as acylating agent.

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