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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 28, 1998 - Issue 18
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Original Articles

A General and Regiospecific Synthesis of 5,8-Disubstituted α-Tetralones

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Pages 3491-3502 | Received 06 Apr 1998, Published online: 22 Aug 2006
 

Abstract

A Pd[0]-mediated Stille coupling strategy was developed to prepare unsymmetrically 5,8-disubstituted α-tetralones in high yield. The compounds synthesized by this route are representative of the ease with which functionality may be introduced into the tetralone core at these positions.

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