Coupling Reaction of Isothiocyanates or Isocyanates with α, β-Unsaturated Esters Mediated by SmI₂

Abstract

α,β-unsaturated ester coupled with isocyanates or isothiocyanates to give the corresponding thioamides or amides in good yields by SmI₂ in the presence of HMPA and t-BuOH in THF at-78°C within a few min.