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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 28, 1998 - Issue 24
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Original Articles

Convenient Synthesis of 7-Bromo-tetrahydro-1,5-benzodiazepin-2-ones

B. Puodẑimūnaitė Institute of Biochemistry, Mokslinink 12, Vilnius, 2600, Lithuania
Pages 4537-4545 | Received 08 Jun 1998, Published online: 22 Aug 2006
 
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Abstract

Treatment of 5-acyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-ones with bromine in the presence of the sulfuric acid afforded products to be brominated exclusively in the aromatic ring at position 7.

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