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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 28, 1998 - Issue 4
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Original Articles

A Facile Route to Cyclic and Acyclic Alkyl-Arginines

Kevin J. Kennedy Department of Pharmaceutical Sciences, Medical University of South Carolina, Charleston, South Carolina, 29425
,
Tiberiu L. Simandan Department of Pharmaceutical Sciences, Medical University of South Carolina, Charleston, South Carolina, 29425
&
Thomas A. Dix Department of Pharmaceutical Sciences, Medical University of South Carolina, Charleston, South Carolina, 29425
Pages 741-746 | Received 13 Aug 1997, Published online: 02 Sep 2006
 
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Abstract

Treatment of commercially available alkyl and cycloalkyl thioureas with methyl iodide provides the corresponding S-alkylisothiouronium iodide which reacts directly with ornithine to yield the title compounds.

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