Synthesis of Some Substituted 2H-Pyrano[3,2-c]pyridine-2,5(6H)-diones. Reaction of Their 3-Acetyl Derivatives with Methyl 3-Amino-2-butenoate

Abstract

Formylation of 4-hydroxy-6-methyl-2(1H)-pyridones and subsequent cyclization with a Wittig reagent or with CH-acidic esters gave a series of title compounds. The same starting pyridones reacted with methyl 3-amino-2-butenoate directly to the corresponding 4,7-dimethylpyrano[3,2-c]pyridines.