Abstract
Triphenylphosphine (TPP)-iodotrimethylsilane (TMSI) was found to be a convenient and highly effective catalyst for the tetrahydropyranylation of aliphatic and aromatic alcohols with dihydropyran in dichloromethane at ambient temperature.
Notes
see ref. 3, 4, and 6.
0.1 M TPP-TMSI solution was prepared by adding iodotrimethylsilane (0.01 mole) freshly made by the reaction of hexamethyldisilane and iodine9 to a solution of triphenylphosphine (0.01 mole) in dichloromethane (100 mL)