Facile Synthesis of 1,3-Diaryl-propanones Through Heck Reaction

Abstract

1,3-diaryl propanones (1a-6a) and 1,3-diaryl-2-carbomethoxy-propanones (1b-6b) have been synthesized through facile palladium catalysed arylation of Baylis- Hillman adducts.

Notes

NMR spectra were recorded at 500 MHz with Brucker 500 NMR spectrometer and at 60 MHz with Hitachi R-600 FT-NMR spectrometer in CDCl₃ using TMS as internal standard, J values are given in Hz. Infrared spectra were recorded on Nicolet Impact-400 FT IR spectrometer. Nicolet spectrometer. All compounds showed satisfactory elemental analysis.