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Abstract
A synthesis of the title compound from dimethyl meso-2,3-dimercapto-succinate and a protected, activated cysteine derivative is described.
Notes
FDA Medical Bulletin: Succimer Approved for Severe Lead Poisoning, Vol. 21, Part 1, p.5, March 1991
Compound 3 consists of a pair of diastereomers due to random attachment of enantiomerically pure cysteine to sulfur on the DMSA carbon with either the R or S configuration. This is true of compounds 7 and 8 as well