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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 2
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Original Articles

Enantioselective Reduction of Ketones by in situ Generated Borane and Cbs Catalyst: Economical Alternative to Bh3-Thf

Alan Ford Department of Chemistry, University of Hull, Cottingham Road, Hull, HXJ6 7RX, United Kingdom
&
Simon Woodward Department of Chemistry, University of Hull, Cottingham Road, Hull, HXJ6 7RX, United Kingdom
Pages 189-192 | Accepted 25 Apr 1998, Published online: 17 Sep 2007
 
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Abstract

The combination of lithium hydride and boron trifluoride diethyl etherate provides a cheap and convenient alternative to other borane sources for the oxazaborolidine catalysed enantioselective reduction of ketones.

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