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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 4
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Original Articles

An Efficient Synthesis Of 6-Substituted 2-(2H-[1,2,4]Triazol-3-Ylmethyl)-1,2,3,4-Tetrahydro-Isoquinolines

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Pages 645-653 | Received 13 Jul 1998, Published online: 17 Sep 2007
 

Abstract

A synthesis of 6-nitro and 6-amino 2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolines using a bis-alkylation process is described. 5-(Aminomethyl)-1-(p-methoxybenzyl)-triazole was prepared by a regioselective route from 1,2,4-triazole.

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