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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 22
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Original Articles

An Alternative Synthesis of Quindoline and one of its Closely Related Derivatives

D. Csányi Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, POBox 17, H-1525, Budapest
,
G. Timári Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, POBox 17, H-1525, Budapest; CHINOIN Pharmaceutical and Chemical Works Co. Ltd., P.O. Box 110, H-1325, Budapest, Hungary
&
Gy. Hajós Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, POBox 17, H-1525, Budapest
Pages 3959-3969 | Received 12 Oct 1998, Published online: 17 Sep 2007
 
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Abstract

The alkaloid Quindoline (13) and one of its tetracyclic isomer indazolo[2,3-a]quinoline (8) have been synthesised utilising the Pd(0)-catalysed cross-coupling reaction of pivaloylamino phenylboronic acid (2) with substituted quinolines.

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