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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 19
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Original Articles

Simple Method for Benzamidomethylation of Phenols in Water Solution

, &
Pages 3451-3458 | Accepted 11 Feb 1999, Published online: 17 Sep 2007
 

Abstract

Benzamidomethyl ethers ROCH2 NHBz (5) (R = aryl, cyclohexyl and benzyl) were obtained in high yields in reactions of ROH (4) with (benzamidomethy1)tri-ethylammonium chloride 3 as a benzamidomethylation agent. Reactions occurred in water, except reactions of cyclohexyl and benzyl alcohol with 3 that occurred in CHCl3.

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