Direct Oxidative Deprotection of Trimethylsilyl Ethers to their Corresponding Carbonyl Compounds with Bis (trimethylsilyl) Chromate Supported onto Silica Gel in Aprotic Solvent

Abstract

Primary and secondary trimethylsilyl ethers are converted to their carbonyl compounds effeciently using bis (Trimethylsilyl) chromate supported on silica gel in dichloromethane. Benzylic double bonds are not prone to cleavage reactions with this method.