Synthesis Of Cyclopentenones 2- and 2,4-Oxygenated From Furfural

Abstract

2-Benzyloxy-4-methoxy-2-cyclopentenone and 2-benzyloxy-2-cyclopentenone were efficiently prepared using furfuryl alcohol as the starting material. The synthetic route employed in both cases involves the previous preparation of a ketoaldehyde that is subsequently cyclized to the parent cyclopentenone. Each stage of this route involves reactions of very low cost, with simple synthetic procedures and very good yields.