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Archives of Andrology
Journal of Reproductive Systems
Volume 45, 2000 - Issue 1
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Research Article

EFFECT OF SODIUM NITROPRUSSIDE ON MOUSE SPERM MIGRATION IN VITRO

Pages 29-33 | Published online: 09 Jul 2009
 

Abstract

In the present study the effect of sodium nitroprusside, a nitric oxide releaser, on mouse sperm motion behavior was examined. The number of sperm migrating in experimental plate to medium containing sodium nitroprusside in concentration 50 nM was significantly higher than the number migrating to control. This effect was observed after 3 and 5 h of incubation, and it was not time dependent. The presence of sodium nitroprusside in higher concentrations did not cause any visible changes or decrease the migration of sperm. These effects were interpreted as chemokinesis but not chemotaxis of sperm induced by influence of sodium nitroprusside on sperm metabolism and motility.

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