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The International Journal on Orbital Disorders, Oculoplastic and Lacrimal Surgery

Volume 39, 2020 - Issue 1

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Case Report

Orbital AL amyloid

Tiffany Michelle ChanCollege of Medicine, Texas A&M University,Bryan, Texas, USA

Claudia Maria Prospero PonceDepartment of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, USA

Richard Cutler AllenSection of Ophthalmology, University of Texas MD Anderson Cancer Center, Houston, TX, USA;Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA

Diana BellDepartment of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA

Andrew Go LeeCollege of Medicine, Texas A&M University,Bryan, Texas, USA;Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, USA;Section of Ophthalmology, University of Texas MD Anderson Cancer Center, Houston, TX, USA;Department of Ophthalmology, University of Texas Medical Branch, Galveston, TX, USA;Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, NY, USA;Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa, IA, USACorrespondence[email protected]

ABSTRACT

Amyloidosis and lymphoma localized to the ocular adnexa are rare, and their presentation may resemble more common inflammatory conditions such as autoimmune disease or infection, which can protract diagnostic evaluation and delay eventual therapy. In a patient with recalcitrant facial and tooth pain and ophthalmoplegia, evaluation should include careful histopathologic analysis of biopsy specimens. We report a case of orbital AL amyloidosis associated with localized lymphoma that presented with intractable dental pain and progressed to bilateral complete ophthalmoplegia.

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The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

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