Persistent orbital inflammation following complete excision of deep dermoid cysts

ABSTRACT

Piecemeal excision of dermoid cysts carries the risk of implanting epithelial fragments into orbital fat, which is well recognized to continue secreting oily debris, inciting chronic, often granulomatous inflammation. The authors present the clinical and histological details for two patients with persistent lipogranulomatous inflammation for years after piecemeal excision of deep orbital dermoid cysts, in the absence of any residual epithelium. The importance of copious saline lavage – to ‘float-out” and reduce microscopic lipid droplets – is also emphasised.

KEYWORDS:

• Cyst
• dermoid
• excision
• extracellular
• inflammation
• lipids
• orbit
• persistent

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

Professor Geoffrey Rose receives some funding from the National Institute of Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology.