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Original Article

Increased drug sensitivity in Candida albicans cells accumulating 14-methylated sterols

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Pages 481-483 | Accepted 26 Aug 1986, Published online: 09 Jul 2009
 

Abstract

Multiple increases in drug sensitivity were observed in Candida albicans cells that were accumulating 14-methylated sterols as a result of a mutation or clotrimazole treatment. The possibility was suggested that a change in membrane permeability caused by the alteration in sterol composition was responsible for the increased susceptibility.

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