Surgical outcomes and prognostic factors of parasagittal meningioma: a single-center experience 165 consecutive cases

Abstract

Purpose

This study aimed to estimate the prognostic factors, long-term outcomes, and surgical strategies for parasagittal meningioma (PSM) and provide a better understanding of surgical experience.

Materials and methods

Patients (n = 1438) who underwent surgery for meningioma between January 2012 and January 2013 were enrolled in a database. We then identified 165 patients with PSM based on this database.

Results

Of the 165 patients with identified PSMs, 103 were female and 62 were male, with a mean age of 49 years. Univariate analysis revealed that male sex (p = .002), non-World Health Organization (WHO) grade I meningioma (p < .001), treatment history (p = .006), surgical time more than 232 minutes (p = .006), and intraoperative bleeding > 300mL³ (p = .019) were associated with decreased progression-free survival (PFS). Multivariate analysis revealed that sex (hazards ratio [HR] = 3.836, 95% confidence interval [CI] = 1.364–10.794; p = .011], tumour grade (HR = 8.479, 95% CI = 3.234–22.230; p < .001), and surgical time (HR = 3.710, 95% CI = 1.057–13.023; p = .041) were independent factors for PFS. Patients with Simpson grade I-II (p = .015), no-treatment history (p = .006), tumour size < 3cm (p = .005), surgical time < 232 minutes (p = .019), intraoperative bleeding < 300mL³ (p < .001), or WHO grade I meningioma (p = .002) had better follow-up conditions.

Conclusion

Surgery was an effective treatment for PSM, and at the time of final follow-up, patients who received aggressive resection had a substantially higher Karnofsky performance scale score.

KEYWORLDS:

• Parasagittal meningioma
• prognostic factors
• surgical procedure
• outcome

Disclosure statement

No potential conflict of interest was reported by the author(s).