Langerhans cell histiocytosis of the sternum

Hiroyuki Tsuchie Department of Orthopedic Surgery, Akita University School of Medicine, Akita, JapanCorrespondence[email protected]

, MD,

Kyoji Okada Department of Orthopedic Surgery, Akita University School of Medicine, Akita, Japan

Hiroyuki Nagasawa Department of Orthopedic Surgery, Akita University School of Medicine, Akita, Japan

Michihiro Yano Department of Pediatrics, Akita University School of Medicine, Akita, Japan

Hiroshi Nanjyo Department of Pathology, Akita University School of Medicine, Akita, Japan

Yoichi Shimada Department of Orthopedic Surgery, Akita University School of Medicine, Akita, Japan

Abstract

We report a rare case of Langerhans cell histiocytosis involving the sternum. The patient was a 12-year-old girl presenting with anterior chest pain and swelling. Radiographs and computed tomography showed an osteolytic lesion in the sternum. Technetium bone scintigraphy revealed increased uptakes in the sternum, the greater trochanter of the right femur, and the right distal tibia. Incisional biopsy for the sternum lesion was performed, and the histopathologic diagnosis was Langerhans cell histiocytosis. She was treated with chemotherapy and the symptoms disappeared.

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Langerhans cell histiocytosis of the sternum

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Langerhans cell histiocytosis of the sternum

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