![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
Background, Aims. Whether diabetes mellitus affects the prognosis of stroke patients, and whether admission hyperglycemia influences prognosis similarly in diabetic as in non‐diabetic patients is assessed controversially. The aims of the study were: 1) to compare the course of diabetic and non‐diabetic acute stroke patients, and 2) to assess the influence of admission serum glucose levels on case fatality.
Methods. In 57 Austrian medical departments the hospital course of consecutive stroke patients was documented prospectively between June 1999 and October 2000.
Results. Two hundred and ninety‐six (30%) of 992 patients had a history of diabetes mellitus. Intracerebral hemorrhage was more frequent in non‐diabetic patients than diabetic (13% versus 5%, P = 0.0001). Coronary heart disease was more frequent in diabetic than in non‐diabetic patients (35% versus 24%, P = 0.0003). The case fatality was 18% among non‐diabetic and 16% among diabetic patients (P = 0.3559). Among patients who were discharged alive, the Barthel Index increased from 50 to 90 in non‐diabetic and from 45 to 75 in diabetic patients (P = 0.0403). In non‐diabetic patients, admission serum glucose>9.2 mmol/L was associated with a more than 4‐fold increase in case fatality, compared with patients with serum glucose<5.7 mmol/L (P<0.0001).
Conclusions. Diabetic stroke patients need special care since they tend to have a poorer recovery than non‐diabetic patients. Admission hyperglycemia in non‐diabetic acute stroke patients predicts a poor prognosis.
| Abbreviations | ||
| AF | = | atrial fibrillation |
| BI | = | Barthel Index |
| CAD | = | coronary artery disease |
| Hyp | = | arterial hypertension |
| ICH | = | intracerebral hemorrhage |
| NIHSS | = | National Institute of Health Stroke Scale |
| RS | = | Rankin scale |
| Abbreviations | ||
| AF | = | atrial fibrillation |
| BI | = | Barthel Index |
| CAD | = | coronary artery disease |
| Hyp | = | arterial hypertension |
| ICH | = | intracerebral hemorrhage |
| NIHSS | = | National Institute of Health Stroke Scale |
| RS | = | Rankin scale |
Acknowledgement
The study was supported by the Working Group for Cerebrovascular Diseases of the Austrian Cardiologic Society.