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Case Report

PANCYTOPENIA DUE TO VITAMIN B12 DEFICIENCY IN A BREAST-FED INFANT

Pages 365-367 | Received 12 Dec 2006, Accepted 06 Feb 2008, Published online: 09 Jul 2009
 

Abstract

Nutritional B12 deficiency in childhood is an uncommon disorder. Most cases are due to maternal insufficiency, resulting from deficient stores and intake, and is generally seen in exclusively breast fed infants. This report describes a breast-fed infant with megaloblastic anemia secondary to maternal vitamin B12 deficiency. We describe this patient to remind readers that B12 deficiency may cause severe pancytopenia and regression of motor functions. These patients can present with unexpected signs and symptoms, such as developmental delay and regression as in our patient. It is also important to take the nutritional history of both the child and the mother of early prevention and treatment. With early awareness and appropriate measures potentially irreversible neurologic damage can be prevented in the infant.

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