![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
ABSTRACT
Purpose: To describe the incidence and risk factors for ocular hypertension and/or glaucoma in patients with Fuchs heterochromic iridocyclitis (FHC).
Methods: Retrospective analysis of 88 patients with FHC. Kaplan–Meier curves estimated the time to develop cataract and ocular hypertension/glaucoma. Possible prognostic factors were investigated in univariate Kaplan–Meier analyses using the Mantel–Cox logrank test.
Results: At presentation with FHC, 52% of patients had a cataract and 26% of patients had ocular hypertension/glaucoma. The estimated percentage of patients with a cataract or ocular hypertension/glaucoma by 4 years after presentation was 71% (CI: 58–81%) and 39% (CI: 28–51%), respectively. Patients aged ≥50 years had significantly greater risk of developing glaucoma (p = 0.0065). After adjusting for age-group, having a cataract at presentation was associated with increased risk of glaucoma (p = 0.032).
Conclusions: Risk factors for development of ocular hypertension/glaucoma were increasing patient age and having a cataract at presentation with FHC.
Keywords:
DECLARATION OF INTEREST
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.
Funding
LL is supported by a National Health and Medical Research Council Early Career Fellowship (#1109330). The Centre for Eye Research Australia receives Operational Infrastructure Support from the Victorian Government in Australia.