Development of Vitreoretinal Lymphoma in a Patient with Sarcoid Uveitis

ABSTRACT

Purpose

The purpose of this article is to report the first case of primary vitreoretinal lymphoma in a patient with sarcoid uveitis.

Material and Methods

A 63-year-old woman with biopsy-proven sarcoid uveitis diagnosed 7 years ago was presented for a 6-month history of bilateral intermediate uveitis and gait disturbance with cerebral magnetic resonance imaging suggestive of neurosarcoidosis. Because of corticoids resistance, a vitrectomy and a cerebral biopsy were performed. The final diagnosis was primary central nervous system diffuse lymphoma. Patient died despite the chemotherapy with an initial improvement of visual and neurological features.

Conclusion

Ophthalmologists should know that patient followed up with sarcoid uveitis can develop a primary vitreoretinal diffuse large B-cell lymphoma.

Keywords:

• Primary central nervous system lymphoma
• primary vitreoretinal lymphoma
• sarcoidosis
• uveitis
• vitrectomy

Declaration of interest

The authors report no conflict of interest. The authors alone are responsible for the content and writing of the article.