The Impact of COVID-19 on Conjunctival Flora

ABSTRACT

Purpose: This study aims to evaluate the effect of coronavirus disease 2019 (COVID-19) on conjunctival flora in patients hospitalized with COVID-19.

Methods: This prospective, controlled study was conducted between June 2020 and December 2020. The study group consisted of 45 confirmed COVID-19 patients and 43 control subjects. The collected samples were inoculated into the Thioglycollate broth media without delay. The samples with growth were then passed on eosin methylene blue agar, sabouraud dextrose agar, chocolate agar, and 5% sheep blood agar solid media.

Results: The mean age of the COVID-19 patients was 64.24 ± 15.4 years, and the control subjects were 59.72 ± 11.4 years. The culture positivity of conjunctiva samples in COVID-19 patients (95.6%) was statistically significantly higher than control subjects (76.7%) (p = .024). Coagulase-negative staphylococcus and Staphylococcus aureus’ positivity was significantly higher in COVID-19 patients than control subjects (p < .05).

Conclusion: Patients with COVID-19 demonstrate significantly higher culture positivity on conjunctival flora than the control subjects.

KEYWORDS:

• Conjunctiva
• coronavirus
• COVID-19
• eye
• flora

Acknowledgments

The authors have no proprietary or financial interest in any products used. The manuscript was edited by American Manuscript Editors.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Ethics committee

Ethics committee approval was received from the Malatya Clinical Research ethics committee (protocol code: 2020/186).