ABSTRACT
Effect of vitamins A, D3, E and H supplementation on oxidative stress/antioxidant indices in buffaloes suffering from trypanosomosis was investigated. Changes in the oxidative stress parameters viz. protein oxidation (protein carbonyls), lipid peroxidation (LPO), and antioxidant enzymes activities viz. Superoxide dismutase (SOD) and catalase (CAT) were evaluated before and after the supplementation of vitamins A, D3, E and H. The buffaloes suffering from trypanosomosis revealed remarkable alterations in the oxidants/antioxidants balance sifted towards oxidative stress. The buffaloes revealed significantly higher protein carbonyls and LPO activity; while SOD and CAT activity were significantly lower in comparison with the healthy controls. Supplementation vitamins A, D3, E, and H to these animals revealed a significant reduction in protein carbonyls and LPO activity; while a significant increase in SOD and CAT activity were also evident. From the present study, it may be concluded that supplementation of these vitamins can help to ameliorate the oxidants/antioxidants balance towards normalcy, and thus to ensure recovery from trypanosomosis in buffaloes.
Acknowledgments
Authors are thankful to the Dean, COVSc and Dean PGS, DUVASU, Mathura for providing necessary facilities to carry out the study.
Disclosure statement
No potential conflict of interest was reported by the authors.