Predicting of successful implantation at IVF cycles

Abstract

Many of the uterine infertility factors are associated with chronic endometritis. Its prevalence reaches 92.6%. Quality of endometrial transformation during the “implantation window” is the basis of successful fertility. In our retrospective comparative study of 101 in vitro fertilization (IVF) cycles, the efficacy of transvaginal Doppler ultrasound (TVDUS) in predicting successful implantation was evaluated. Inclusion criteria were as follows: age younger than 41 years and good quality of embryos. Exclusion criteria were as follows: 41 and older age, poor quality of embryos and uterine cavity lesions. The 1st group included 38 cases with the presence of endometrial blood flow (EBF). The 2nd group included 63 cases with the absence of EBF. TVDUS was performed before embryo transfer (ET). Significant differences of EBF were connected with age and duration of infertility. In women of less than 31 years old, EBF was detected in 47.4% cases versus 26.3% women of older age. EBF was not detected in 74.6% of the cases of duration of infertility for 5 years and more. Pregnancy rate was significantly higher in the 1st group (63.1% versus 39.7%) and when endometrial thickness was 8–11 mm (52.1% versus 30.0%). We offer routine evaluation of endometrial thickness and EBF with TVDUS as a very helpful approach for predicting the implantation in IVF cycles.

Keywords:

• Efficacy of ET
• endometrial blood flow
• endometritis
• “implantation window”
• IVF failures
• transvaginal Doppler ultrasound

Acknowledgements

We regard special thanks to all clinical staff of Assisted Reproductive Technologies Clinic “Test-tube babies” for personal assistance and colleagues from Russian Peoples’ Friendship University for helpful advice in working out of this survey.

Declaration of interest

The authors report no declarations of interest.