Papillary thyroid carcinoma in Struma Ovarii

Abstract

Struma Ovarii is one of the types of mature teratoma, with predominant thyroid tissue (>50%). It occurs in 1% of all cases of ovarian tumors and in 2.7% of dermoid tumors. There are no specific clinical, radiological or serum markers for this rare pathology. Rarely it may be accompanied by ascites and the increased level of CA-125. In general Stuma Ovarii is clinically defined as an ovarian malignancy. It is diagnosed only by histopathological examination of the surgical material. Diagnosis of Struma Ovarii dictates the need for advanced research of the thyroid. Struma Ovarii is mostly benign. Its malignant transformation occurs in only 5% of all cases, That leads to further management planning analogous to the treatment of thyroid cancer. The case of malignant Struma Ovarii of the 50-year-old woman, which led to total thyroidectomy and radioactive iodine therapy – is described.

摘要

卵巢甲状腺肿是成熟畸胎瘤的一种类型, 以甲状腺组织为主(>50%)。它发生在所有卵巢肿瘤的1%和皮样肿瘤的2.7%。目前没有针对这种罕见病理的特定临床、影像学或血清标志物。很少伴有腹水和CA-125水平升高。一般而言, 卵巢甲状腺肿在临床上被定义为卵巢恶性肿瘤。只有通过手术取材的组织病理学检查才能确诊。卵巢甲状腺肿的诊断要求对甲状腺进行深入研究。卵巢甲状腺肿大部分是良性的。其恶变仅发生占所有病例的5%, 这导致了类似于甲状腺癌治疗的进一步管理计划。本文描述了一位50岁女性患恶性卵巢甲状腺肿, 并行甲状腺全切和放射性碘治疗的病例。

The Chinese abstracts are translated by Prof. Dr. Xiangyan Ruan and her team: Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

Keywords:

• Papillary thyroid carcinoma
• Struma Ovarii
• thyroid multinodular hyperplasia

Acknowledgements

We acknowledge the laboratory staff of Al. Natishvili Institute of Morphology, TSU – for preparation of specimens for histological and immunohistochemical investigations.

Disclosure statement

The authors declare that they have no competing interests. The authors do not have any commercial or collaborative relationships that could be constructed as biased or inappropriate.