Influence of one-day diabetes mellitus clinic management on blood glucose control and prognosis in patients with gestational diabetes mellitus

Abstract

Objective

To explore the influence of the one-day diabetes mellitus (DM) clinic management model on blood glucose control and prognosis in patients with gestational diabetes mellitus (GDM).

Methods

A total of 930 patients diagnosed with GDM by oral glucose tolerance test screening at 24–28 weeks of gestation were selected from those who underwent outpatient prenatal checkups at our hospital and were randomly divided into one-day DM clinic group (n = 509) and control group (n = 421). A one-day DM clinic intervention was conducted in the one-day DM clinic group, and individualized dietary interventions and exercise instruction were given in the control group.

Results

The compliance rates of fasting blood glucose and two-hour postprandial blood glucose (2-h PPBG) were higher in the one-day DM clinic group than in the control group (p < .05). The compliance rates of the oral glucose tolerance test and insulin release test were higher in the one-day DM clinic group than in the control group (p < .05). There existed statistically significant differences in fasting blood glucose before delivery, together with the difference between fasting blood glucose at enrollment and before delivery and the difference between glycated hemoglobin at enrollment and before delivery (p < .05).

Conclusion

The one-day diabetes mellitus clinic management model is more conducive to blood glucose control in patients with GDM and more conducive to the recovery of blood glucose and islet function in patients with GDM after delivery and to reduce the occurrence of adverse pregnancy outcomes.

1日糖尿病门诊管理对妊娠期糖尿病患者血糖控制及预后的影响 摘要

目的:探讨1日糖尿病门诊管理模式对妊娠期糖尿病(GDM)患者血糖控制及预后的影响。

方法:选取来我院门诊产前检查的妊娠24-28周孕妇, 经口服糖耐量检查诊断为GDM的患者930例, 随机分为1日糖尿病门诊组(n=509)和对照组(n=421)。1日糖尿病门诊组进行1日糖尿病门诊干预, 对照组给予个体化饮食干预和运动指导。

结果:1日糖尿病门诊组空腹血糖和餐后2小时血糖(2h PPBG)依从率高于对照组(p<0.05)。口服糖耐量试验和胰岛素释放试验的依从率在1日糖尿病临床组高于对照组(p<0.05)。分娩前空腹血糖、入组基线和分娩前空腹血糖变化、入组基线和分娩前糖化血红蛋白差异均有统计学意义(p<0.05)。

结论:1日糖尿病门诊管理模式更有利于GDM患者的血糖控制, 有助于GDM患者分娩后血糖和胰岛功能的恢复, 减少不良妊娠结局的发生。

Keywords:

• Gestational diabetes mellitus
• one-day diabetes mellitus clinic
• blood glucose control
• Perinatal outcomes

Disclosure statement

The authors report no conflicts of interest in this work.