https://orcid.org/0000-0001-5805-5643
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Abstract
Objective
We aim to explore the contributing factors of clinical pregnancy outcomes in PCOS patients undergoing their first FET treatment.
Methods
A retrospective analysis was conducted on 574 PCOS patients undergoing their first FET treatment at a private fertility center from January 2018 to December 2021.
Results
During the first FET cycle of PCOS patients, progesterone levels (aOR 0.109, 95% CI 0.018-0.670) and endometrial thickness (EMT) (aOR 1.126, 95% CI 1.043-1.419) on the hCG trigger day were associated with the clinical pregnancy rate. Similarly, progesterone levels (aOR 0.055, 95% CI 0.007-0.420) and EMT (aOR 1.179, 95% CI 1.011-1.376) on the hCG trigger day were associated with the live birth rate. In addition, AFC (aOR 1.179, 95% CI 1.011-1.376) was found to be a risk factor for preterm delivery.
Conclusions
In women with PCOS undergoing their first FET, lower progesterone levels and higher EMT on hCG trigger day were associated with clinical pregnancy and live birth, and AFC was a risk factor for preterm delivery. During FET treatment, paying attention to the patient’s endocrine indicators and follicle status may have a positive effect on predicting and improving the pregnancy outcome of PCOS patients.
Disclosure statement
The authors declare that they have no competing interests or relevant relationships.
Authors’ contributions
S.L., T.L.Y. designed the study. S.X., M.L.M., X.C. conducted data collection and supervised the study. X.C., L.H. analyzed the data. X.C. drafted the original manuscript. S.L., T.L.Y., L.H. revised the paper.
Data availability statement
The datasets used and/or analyzed during the current study available from the corresponding author on reasonable request.