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Abstract
The relationship between lipids and the haemostatic mechanisms participating in the evolution of the atherosclerotic plaque have been undergoing extensive investigation for over a century. Circulating lipoproteins can enhance platelet activity. Among these lipid fractions, lipoprotein (a) (Lp(a)), a predictor of atherosclerotic disease, has been proposed as a link between lipids and haemostasis. In this review, we briefly consider lipid-platelet, and particularly Lp(a)-platelet, interactions which may be relevant to the pathogenesis of atherosclerotic disease and its complications.