Uncertainty of fast biological radiation dose assessment for emergency response scenarios

Abstract

Purpose: Reliable dose estimation is an important factor in appropriate dosimetric triage categorization of exposed individuals to support radiation emergency response.

Materials and methods: Following work done under the EU FP7 MULTIBIODOSE and RENEB projects, formal methods for defining uncertainties on biological dose estimates are compared using simulated and real data from recent exercises.

Results: The results demonstrate that a Bayesian method of uncertainty assessment is the most appropriate, even in the absence of detailed prior information. The relative accuracy and relevance of techniques for calculating uncertainty and combining assay results to produce single dose and uncertainty estimates is further discussed.

Conclusions: Finally, it is demonstrated that whatever uncertainty estimation method is employed, ignoring the uncertainty on fast dose assessments can have an important impact on rapid biodosimetric categorization.

Keywords:

• Biodosimetry
• retrospective dosimetry
• radiation
• triage screening
• uncertainty

Acknowledgements

The authors would also like to express our thanks to the rest of our RENEB, MULTIBIODOSE and EURADOS colleagues, particularly the management boards, for supporting this work.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.