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Research Article

RENEB – Running the European Network of biological dosimetry and physical retrospective dosimetry

Ulrike KulkaBundesamt für Strahlenschutz, Department Radiation Protection and Health, Oberschleissheim, Germany; Correspondence[email protected]

Michael AbendBundeswehr Institute of Radiobiology affiliated to the University of Ulm, Munich, Germany;

Elizabeth AinsburyPublic Health England, CRCE, Chilton, Didcot, Oxon, UK;

Christophe BadiePublic Health England, CRCE, Chilton, Didcot, Oxon, UK;

Joan Francesc BarquineroUniversitat Autònoma de Barcelona, Barcelona, Spain;

Lleonard BarriosUniversitat Autònoma de Barcelona, Barcelona, Spain;

Christina BeinkeBundeswehr Institute of Radiobiology affiliated to the University of Ulm, Munich, Germany;

Emanuela BortolinIstituto di Superiore di Sanità, Rome, Italy;

Alexandra CucuInstitutul National de Sanatate Publica, Romania;

Andrea De AmicisArmy Medical and Veterinary Research Center, Rome, Italy;

Inmaculada DomínguezUniversity of Sevilla, Seville, Spain;

Paola FattibeneIstituto di Superiore di Sanità, Rome, Italy;

Anne Marie Frøvig,Norwegian Radiation Protection Authority, Oslo, Norway;

Eric GregoireInstitut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France;

Kamile GuogyteRadiation Protection Center, Vilnius, Lithuania;

Valeria HadjidekovaNational Center for Radiobiology and Radiation Protection, Bulgaria;

Alicja JaworskaNorwegian Radiation Protection Authority, Oslo, Norway;

Ralf KriehuberForschungszentrum Jülich, Germany;

Carita LindholmRadiation and Nuclear Safety Authority, Helsinki, Finland;

David Lloydaffiliated to Public Health England, CRCE, Chilton, Didcot, Oxon, UK;

Katalin LumniczkyNational Public Health Centre – National Research Directorate for Radiobiology and Radiohygiene, Budapest, Hungary;

Fiona LyngDublin Institute of Technology, Dublin, Ireland;

Roberta MeschiniUniversity of Tuscia, Viterbo, Italy;

Simone MörtlHelmholtzZentrum München, Oberschleissheim, Germany;

Sara Della MonacaIstituto di Superiore di Sanità, Rome, Italy;

Octávia Monteiro GilCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Bobadela-LRS, Portugal;

Alegria MontoroHospital Universitario y Politécnico la Fe de la Comunidad Valenciana, Valencia, Spain;

Jayne MoquetPublic Health England, CRCE, Chilton, Didcot, Oxon, UK;

Mercedes MorenoServicio Madrileño de Salud – Hospital General Universitario Gregorio Marañón, Madrid, Spain;

Ursula OestreicherBundesamt für Strahlenschutz, Department Radiation Protection and Health, Oberschleissheim, Germany;

Fabrizio PalittiUniversity of Tuscia, Viterbo, Italy;

Gabriel PanteliasNational Centre for Scientific Research Demokritos, Athens, Greece;

Clarice PatronoAgenzia Nazionale per le Nuove Tecnologie, ĹEnergia e lo Sviluppo Economico Sostenibile, Rome, Italy;

Laure Piqueret-StephanPROCyTOX, Commissariat à l’Energie Atomique et aux Energies Alternatives, Fontenay-aux-Roses, and Université Paris-Saclay, Paris, France;

Matthias PortBundeswehr Institute of Radiobiology affiliated to the University of Ulm, Munich, Germany;

María Jesus PrietoServicio Madrileño de Salud – Hospital General Universitario Gregorio Marañón, Madrid, Spain;

Roel QuintensBelgian Nuclear Research Center, Mol, Belgium;

Michelle RicoulPROCyTOX, Commissariat à l’Energie Atomique et aux Energies Alternatives, Fontenay-aux-Roses, and Université Paris-Saclay, Paris, France;

Horst RommBundesamt für Strahlenschutz, Department Radiation Protection and Health, Oberschleissheim, Germany;

Laurence RoyInstitut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France;

Géza SáfrányNational Public Health Centre – National Research Directorate for Radiobiology and Radiohygiene, Budapest, Hungary;

Laure SabatierPROCyTOX, Commissariat à l’Energie Atomique et aux Energies Alternatives, Fontenay-aux-Roses, and Université Paris-Saclay, Paris, France;

Natividad SebastiàHospital Universitario y Politécnico la Fe de la Comunidad Valenciana, Valencia, Spain;

Sylwester SommerInstitut Chemii i Techniki Jadrowej, Warsaw, Poland;

Georgia TerzoudiNational Centre for Scientific Research Demokritos, Athens, Greece;

Antonella TestaAgenzia Nazionale per le Nuove Tecnologie, ĹEnergia e lo Sviluppo Economico Sostenibile, Rome, Italy;

Hubert ThierensUniversiteit Gent, Faculty of Medicine and Health Sciences, Gent, Belgium;

Istvan Turaiaffiliated to National Public Health Centre – National Research Directorate for Radiobiology and Radiohygiene, Budapest, Hungary;

François TrompierInstitut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France;

Marco ValenteFrench Army Biomedical Research Institute, France;

Pedro VazCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Bobadela-LRS, Portugal;

Philippe Voisinaffiliated to Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France;

Anne VralUniversiteit Gent, Faculty of Medicine and Health Sciences, Gent, Belgium;

Clemens WodaHelmholtzZentrum München, Oberschleissheim, Germany;

Demetre ZafiropoulosLaboratori Nazionali di Legnaro, Padua, Italy;

Andrzej WojcikStockholm University, Centre for Radiation Protection Research, Stockholm, Sweden

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Abstract

Purpose: A European network was initiated in 2012 by 23 partners from 16 European countries with the aim to significantly increase individualized dose reconstruction in case of large-scale radiological emergency scenarios.

Results: The network was built on three complementary pillars: (1) an operational basis with seven biological and physical dosimetric assays in ready-to-use mode, (2) a basis for education, training and quality assurance, and (3) a basis for further network development regarding new techniques and members. Techniques for individual dose estimation based on biological samples and/or inert personalized devices as mobile phones or smart phones were optimized to support rapid categorization of many potential victims according to the received dose to the blood or personal devices. Communication and cross-border collaboration were also standardized. To assure long-term sustainability of the network, cooperation with national and international emergency preparedness organizations was initiated and links to radiation protection and research platforms have been developed. A legal framework, based on a Memorandum of Understanding, was established and signed by 27 organizations by the end of 2015.

Conclusions: RENEB is a European Network of biological and physical-retrospective dosimetry, with the capacity and capability to perform large-scale rapid individualized dose estimation. Specialized to handle large numbers of samples, RENEB is able to contribute to radiological emergency preparedness and wider large-scale research projects.

Keywords:

Acknowledgements

This work was supported by the European Commission (FP7, GA 295513). We explicitly thank Susan Fischer for excellent assistance and administrative support. We express our gratitude for the valuable support and encouragement from the Advisory Board members – Elena Buglova, Zhanat Carr, Eduardo Herrera-Reyes, David Lloyd, Istvan Turai and Philippe Voisin. Last, not least, the enthusiasm and passion of all partners and candidates for this project cannot be emphasized enough, this is what made RENEB possible.

Disclosure statement

The authors report no conflicts of interest. The authors alone are response for the content and writing of the paper.

RENEB – Running the European Network of biological dosimetry and physical retrospective dosimetry

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RENEB – Running the European Network of biological dosimetry and physical retrospective dosimetry

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