An Attempt to Assess the Activity of Tumour Cells by the Study of Nucleolar Morphology, Mitotic Index and Phosphorus with ³²P

S. Mitra Department of Cell Research, Chittaranjan National Cancer Research Centre, Calcutta

P. De Department of Cell Biophysics, Chittaranjan National Cancer Research Centre, Calcutta

R. Chatterjee Department of Cell Research, Chittaranjan National Cancer Research Centre, Calcutta

K. Bhattacharya Department of Cell Biophysics, Chittaranjan National Cancer Research Centre, Calcutta

A. Bose Department of Cell Research, Chittaranjan National Cancer Research Centre, Calcutta

H. Dutta Department of Cell Biophysics, Chittaranjan National Cancer Research Centre, Calcutta

Summary

(1) A technique has been established for the determination of ³²P uptake of the average tumour cell.

(2) A correlation was observed between nucleolar morphology, mitotic index and ³²P uptake of an average tumour cell of a particular type of tumour.

(3) All the above factors increased consistently from the benign tumour to adeno-carcinoma which retains some amount of differentiation in the form of persistent acinar space and finally to carcinoma simplex where the differentiation is minimum.

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An Attempt to Assess the Activity of Tumour Cells by the Study of Nucleolar Morphology, Mitotic Index and Phosphorus with ³²P

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An Attempt to Assess the Activity of Tumour Cells by the Study of Nucleolar Morphology, Mitotic Index and Phosphorus with 32P

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An Attempt to Assess the Activity of Tumour Cells by the Study of Nucleolar Morphology, Mitotic Index and Phosphorus with ³²P