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Original Article

Studies on Cell-survival of Irradiated Ehrlich Ascites Tumour

I. The Effect of the Host's Age and the Presence of Non-viable Cells on Tumour Takes

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Pages 127-134 | Received 20 Dec 1960, Published online: 03 Jul 2009
 

Summary

(1) An average inoculum of as little as 1·4 cells of a tetraploid Ehrlich ascites tumour has been found sufficient to give rise to 50 per cent tumour takes in new-born mice.

(2) The number of inoculated cells necessary to produce a tumour increases rapidly with the age of the host mice.

(3) The viability of the tumour cells did not appear to be affected when they were inoculated in a mixture with heavily-irradiated tumour cells.

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