Summary
It is shown that in hypophysectomized frogs the aggregated melanophore pigment will expand in response to moderate total-body x-irradiation. The effect is shown to be mediated by the liberation of neurohormones, and serotonin is indicated specially. The methods were partial shielding, paper chromatography of the renal excretion on serotonin after x-irradiation and reflection photometry of small pieces of frog's skin.