Radiation Damage and the Surface Properties of Ehrlich Ascites-tumour Cells

Summary

Mice bearing Ehrlich ascites tumours were injected intraperitoneally with ¹³¹I-tagged protein at intervals after a whole-body dose of 1400 rads of x-rays. This lethal dose of x-rays had no effect on penetration of the protein into the tumour cells at intervals of 4, 24 and 48 hours, and immediately after irradiation. Transport of the protein from the peritoneal cavity to the rest of the body of the mouse was, however, progressively retarded after irradiation.